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Putrescine Restoration Kit

Putrescine Restoration Kit


Putrescine is a foul-smelling organic chemical compound (biological amine) that occurs from the natural breakdown of amino acids and is responsible for the horrible smell of putrefying flesh, bacterial vaginosis, and halitosis. It is also found in minute quantities in our sperm and can be a marker for determining bacterial vaginosis (odor was strongly associated with increased levels of putrescine) diagnosis. Putrescine fulfills essential physiological functions in a wide variety of living cells.

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Putrescine shows many physiological functions, and it is a precursor in the synthesis of other polyamines (spermine and spermidine). Physiological functions of putrescine and other polyamines are related to their polycationic nature, which determines interactions with negatively charged molecules such as DNA, RNA, proteins, phospholipids. Putrescine is however toxic in large amounts and must be detoxified by enzymes (diamine oxidase and aldehyde dehydrogenase for example) and are expressed through urine.

Putrescine production within reason is very important for proper digestive health. Ingestion of protein increases colony forming units of probiotic bacteria including Bifidobacteria and Lactobacillus that are able to ferment protein. Increasing probiotic bacteria colony forming units of Bifidobacteria increases production of the short chain fatty acids butyrate which helps to feed our coloncytes, relieve leaky gut, and relieve gastrointestinal inflammation. However, if you are suffering from bacterial dysbiosis of bacteria that can ferment protein a greater catabolism of amino acids occurs with the digestive tract instead of being metabolized by our bodies. Larger amounts of protein being fermented by our microbiome causes increased putrescine production and foul-smelling breath, gas, and stool. If you have too many of these organisms and you eat a diet high in protein (animal meat, eggs, cheese, nuts, beans), then excessive protein fermentation may occur, leading to increase putrescine. You might also develop symptoms including bloating, excessive smelly flatulence, belching, halitosis, gastrointestinal reflux (from increased abdominal pressure), hiatal hernia (from increased abdominal pressure), and abdominalpain.